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Unlocking the Body's Rhythm: How UC Irvine's Research Could Revolutionize Cancer Treatment

Issue # 0173

Author

Joshua Tjia
29 May

In this Irvine Insider Issue . . .

😁 Laugh Of The Day

🌤️ Irvine Weather

⏰🛌 Unlocking the Body's Rhythm: How UC Irvine's Research Could Revolutionize Cancer Treatment

🎼🩵 Pacific Symphony Presents 'Music of Hope' to Honor Cancer Survivors at South Coast Plaza

👶🍼 Last Week to Support the Irvine 2/11 Marine Adoption Committee Baby Gift Drive

🎠🍊This Week at Great Park: Free Balloon Rides, Art Exhibition, Farmer's Market, and More

📖✨ Lakeside Middle School's Academic Pentathlon Team Achieves 2nd Place at National Championships

🍄🍴 Mushrooms: The Superfood Powerhouse for Stroke Prevention and Overall Health

🧯Stay Safe: Essential Wildfire Preparedness Tips for Orange County Residents

🎨🧑‍🎨 Don't Miss the 30th Annual Studio Arts Festival: A Day of Art and Community

🎼🎼 Upcoming High School Music Calendar

🐥🐣 Protect Our Ducklings: Important Guidelines for Their Safety in Irvine

⚾️ UC Irvine Baseball Team Advances to NCAA Regionals for the First Time Since 2021

🏃🏽‍♂️ UC Irvine Men's Track & Field Team Concludes NCAA West First Round with Strong Performances

🏀🏐🎾⚾ UCI Anteaters Upcoming Home Games

⚾️ Irvine Valley's Own Jack Haggerty Makes Waves at University of Texas Permian Basin

🏀🏀 Upcoming home games for the IVC LASERS

🏀 Crean Lutheran Welcomes Kyle Rouse as New Head Coach for Girls' Basketball Team

🏈🎾 High School Athletics Calendar

🚔💵 Irvine Police Arrest Man with $2,700 in Counterfeit Money and Stolen Credit Cards

🍏🥭🍑 Local Farmers Markets

🌟🏪🎉Irvine’s Best Kept Secrets: Is Your Business One of Them?

📅📅 Lots of Local Events

📞💡 Useful Contact Information

How did the sunflower salesman earn a living?

It went from door to door petaling its wares.

We hope this joke brings some laughter to your day! 😁

Unlocking the Body's Rhythm: How UC Irvine's Research Could Revolutionize Cancer Treatment

A research team at UC Irvine discovered that leveraging the circadian clock can enhance the efficacy of checkpoint inhibitor cancer therapy. Published in Nature Immunology, the study shows that timing immunotherapy based on an individual's circadian patterns improves treatment outcomes. The team found that circadian disruption promotes cancer by increasing inflammation and immunosuppressive cells. Using single-cell RNA sequencing in colorectal cancer models, they identified that targeting therapy when these cells are most abundant enhances its effectiveness. This breakthrough suggests personalized treatment strategies could be developed by aligning with the body's natural rhythms.

Pacific Symphony Presents 'Music of Hope' to Honor Cancer Survivors at South Coast Plaza

Through June 10, Pacific Symphony and community musicians will perform "Music of Hope" at South Coast Plaza’s Jewel Court, dedicated to everyone affected by cancer. This event, featuring pianist Hye-Young Kim and violinist Madalyn Parnas Möller, aims to honor cancer survivors. Special thanks is given to South Coast Plaza and Yamaha Music USA for their support.

#MusicOfHope

Last Week to Support the Irvine 2/11 Marine Adoption Committee Baby Gift Drive

There is only one week left to donate to the Irvine 2/11 Marine Adoption Committee, Inc. Baby Gift Drive. They are collecting new, unopened baby essentials for the 2/11 Marine Battalion families at Camp Pendleton. Needed items include:

  • burp cloths

  • lotions

  • soaps

  • newborn gowns

  • onesies

  • receiving blankets

  • infant car seats

  • pack and plays

  • highchairs

  • baby clothes (sizes 0-18 months)

Donations can be dropped off at Irvine City Hall or the Great Park Visitors Center during business hours. For a complete list and more information, visit irvine211marines.org.

#WeAreIrvine #SupportMarineFamilies #BabyGiftDrive

This Week at Great Park: Free Balloon Rides, Art Exhibition, Farmer's Market, and More

- Free rides on the Great Park Balloon (Thursday–Sunday)

- "California Landscapes: Then & Now" exhibition at the Great Park Gallery (Thursday–Sunday)

- Storybook Time in the Farm for kids and parents (Sunday, June 2, 10–10:30 a.m. and 10:45–11:15 a.m.)

- Great Park Certified Farmer's Market with fresh local produce (Sunday, June 2, 10 a.m.–2 p.m., Parking Lot 2)

- Find classes and activities for all ages at yourirvine.org

Lakeside Middle School's Academic Pentathlon Team Achieves 2nd Place at National Championships

Lakeside Middle School’s Academic Pentathlon team secured 2nd place at the National Championships, following their 2nd place win at State! The team, including Esther Ahn, Claire Karimi, Hanging Li, Katie Nagai, Brian Quinonez, Joshua Robertson, Amogh Sharma, Rudra Thakur, and Yun Jen Yeh, competed in fine arts, literature, mathematics, science, and social science. Esther, Katie, Joshua, and Yun Jen also received individual medals. Congratulations to these outstanding students! Learn more at iusd.org/USAcademicPentathlon2024.

Mushrooms: The Superfood Powerhouse for Stroke Prevention and Overall Health

Mushrooms are a superfood with powerful disease-fighting properties, especially for stroke prevention. They are low-sodium, low-calorie, fat-free, and cholesterol-free, packed with fiber, vitamins, and minerals. Different types of mushrooms provide various health benefits, including antioxidants to protect brain cells, anti-inflammatory properties, beta glucan to improve cholesterol, B vitamins for red blood cell production, copper for healthy bones and nerves, and potassium to lower blood pressure. They may also protect against neurodegenerative diseases like Alzheimer's and Parkinson’s. Enjoy recipes from UCI Health featuring these mushrooms: crispy wild mushroom tacos, mushroom and spinach farro risotto, and sukiyaki with assorted mushrooms, all showcasing their health benefits and delicious flavors.

Stay Safe: Essential Wildfire Preparedness Tips for Orange County Residents

Over the past 20 years, Orange County has experienced a rise in destructive wildfires affecting communities and natural landscapes. The Irvine Ranch Conservancy, OC Parks, the City of Irvine, the City of Newport Beach, and the Orange County Fire Authority (OCFA) are collaborating to protect resources. Key wildfire safety measures include:

  • staying alert during Red Flag Warnings

  • reporting threats to 911

  • reducing home wildfire hazards using OCFA's survey

  • managing vegetation

  • knowing evacuation protocols

  • preparing a household fire plan and a go-bag with supplies for at least 72 hours

While not all wildfires can be prevented, increased awareness and preparedness help mitigate risks, with IRC and partners actively monitoring and minimizing fire dangers.

Don't Miss the 30th Annual Studio Arts Festival: A Day of Art and Community

Join the community on Saturday, June 1, for the 30th Annual Studio Arts Festival at Heritage Community Park from 9 a.m. to 5 p.m. Attendees can explore unique, handcrafted pieces from over 100 Southern California artists. Admission and parking are free. More details are available at cityofirvine.org/studioartsfestival.

#IrvineStudioArtsFestival #ShopLocal #SupportArtists #30thAnniversary #IrvineFineArts #ArtHappensHere #WeAreIrvine

Upcoming Northwood High School’s Music Calendar

No events scheduled for May.

For the latest updates or additional details, please visit https://timbmusic.org/events/

Upcoming University High School's Choirs Calendar

No events scheduled for May.

For the latest updates or additional details, please visit https://www.uhschoirs.org/2023-24-season.html

Upcoming Woodbridge High School's Music Calendar

No events scheduled for May.

For the latest updates or additional details, please visit https://www.whs-music.org/

Upcoming Woodbridge High School’s Vocal Music Calendar

  1. May 31st, 7 PM: Broadway Rocks Concert

For the latest updates or additional details, please visit https://woodbridgechoirs.weebly.com/calendar.html

Upcoming Irvine High School's Music Calendar

No events scheduled for May.

For the latest updates or additional details, please visit https://www.vimb.info/calendar

Upcoming Irvine High School's Choral Calendar

  1. Tues & Wed, May 28 & 29, 3:30-6:30 PM: Dress rehearsal “Voices” (All Choirs) at IHS Theater.

  2. Thurs.- Sat, May 30-June 1, 7:00 PM: Voices 2024 (All Choirs) at IHS Theater.

  3. Wed, June 5, 7:00 PM: Heritage Awards (Chorale) at IHS Gym.

For the latest updates or additional details, please visit https://www.ihschoralmusic.org/calendar.html

Protect Our Ducklings: Important Guidelines for Their Safety in Irvine

  • Admire ducklings from a distance as handling them can be harmful and illegal.

  • If you find a stuck or abandoned duckling, call Irvine Animal Services at 949-724-7092 for help.

  • Avoid feeding or watering them to prevent choking. Let’s be responsible and ensure their safety.

#Ducklings #IrvineAnimals #WeAreIrvine #WildlifeReminders #WildlifeCareTips

UC Irvine Baseball Team Advances to NCAA Regionals for the First Time Since 2021

UC Irvine baseball received an at-large bid to the NCAA Regionals and will compete in the Corvallis Regional. This marks their first postseason appearance since 2021 and their second under head coach Ben Orloff. UCI finished the regular season with a 43-12 record, tying the program's most regular-season wins, and placed second in the Big West with a 22-8 record. This is UCI's 10th postseason appearance as a Division I program and their eighth at-large bid. In Corvallis, they will face hosts Oregon State, Tulane, and their first-round opponent, Nicholls, whom they will meet for the first time. Play begins on May 31, with games broadcast on ESPN+ and KUCI 88.9 FM.

UC Irvine Men's Track & Field Team Concludes NCAA West First Round with Strong Performances

The UC Irvine men's track & field team concluded their participation in the NCAA West First Round at John McDonnell Field. Junior Jacob Hawkins finished 27th in the discus with a throw of 54.39 meters, marking the end of a record-breaking season. Senior Justin Willingham placed 30th in the discus and ended his collegiate career as UCI's all-time leader in the shot put. Both Hawkins and Willingham also competed in the shot put earlier in the week. Sophomore Kenechukwu Okonkwo finished 36th in the triple jump with a leap of 14.60 meters, after a season that saw him rise to No. 3 on UCI's all-time list. The season continues for Josh Farmer, who will compete in the decathlon at the NCAA Championships in June.

UCI Anteaters Upcoming Home Games

No upcoming UCI home games

Irvine Valley's Own Jack Haggerty Makes Waves at University of Texas Permian Basin

Former Irvine Valley baseball standout Jack Haggerty had a stellar season at the University of Texas Permian Basin, where he played as an outfielder. The Falcons ended their historic season on May 19, with a high-scoring game against Lubbock Christian, finishing with a record 35 wins and a first-ever NCAA Tournament game victory. Haggerty, named second team all-Lone Star Conference, batted .364, scored 60 runs, and had 72 hits, including 11 doubles, two triples, and a home run. He recorded 41 RBIs, a .455 slugging percentage, and a .490 on-base percentage, while stealing 13 bases. His previous season stats included a .339 batting average and a .874 OPS. During his 2022 season with IVC, he had a .359 batting average and was second on the team in several categories.

🏐⚽🏀 Upcoming home games for the IVC LASERS

No upcoming IVC home games

Crean Lutheran Welcomes Kyle Rouse as New Head Coach for Girls' Basketball Team

Crean Lutheran High School has appointed Kyle Rouse as the new head girls' basketball coach. Rouse brings over 20 years of coaching experience, having previously led Westcliff University’s women’s basketball team to significant achievements, including a NAIA National Tournament berth and a California Pacific Conference Tournament Championship appearance. Known for his dedication to both athletic and academic excellence, Rouse organized the highest team GPA in program history at Westcliff. Athletic Director Eric Olson praised Rouse’s strategic vision and commitment to excellence, aligning with the school’s mission. Rouse holds a Master’s in Coaching and Athletics Administration and a Bachelor’s in Sociology/Leadership. He expressed excitement about building a program that excels both on and off the court at Crean Lutheran.

High School Athletics Calendar -

** Updated With May Schedule

Upcoming Irvine High School’s Varsity home games:

No upcoming home games.

Irvine Police Arrest Man with $2,700 in Counterfeit Money and Stolen Credit Cards

Spectrum Officers arrested Johnny Lucero Berlino, 31, of Huntington Beach, after finding $2,700 in counterfeit money, stolen mail, and credit cards belonging to other people in his vehicle, which was identified as lost or stolen. The investigation revealed the car was purchased with counterfeit money and was an unreported stolen vehicle. Berlino, on parole for auto theft, was booked at Orange County Jail on multiple felony charges.

#dontcommitcrimeinirvine #irvine #irvinepolice #irvinepd #police #lawenforcement #cityofirvine #orangecounty #policeofficer #policework

Irvine’s Best Kept Secrets: Is Your Business One of Them?

We know our community is brimming with businesses that have fascinating stories and big hearts. If you’re a local business owner making waves, crafting unique experiences, or simply putting a smile on our faces, we want to chat with you! “Irvine Insider” is eager to shine a light on the unsung heroes of our city. Let’s collaborate and let the community know what makes your business special.

Click the link below and fill out the Local Business Spotlight Application Form to be featured and let’s celebrate the spirit of Irvine together!

Irvine Insider is sent to a local audience of Irvine residence Monday through Friday with 55% - 60% open rate. Our newsletter is a great way to reach Irvine residents.

  • Kaiser Permanente Irvine Farmers Market

  • Saturday Farmers Market at Mariners Church Irvine

    • When: Saturday, 8 AM - 12 PM

    • Where: 5428 Bonita Canyon Dr, Irvine, CA 92603

  • Great Park Certified Farmers Market

  • Manassero Farmers

    • When: Daily, 9 AM - 4:30 PM

    • Where: 33 Irvine Valley, Irvine, CA 92604

  • Tanaka Farms

    • When: Daily, 9 AM - 5 PM

    • Where: 5380 3/4 University Dr, Irvine, CA 92612

    • More Info: Tanaka Farms

June 1 2024 Studio Arts Festival 9 AM - 5 PM

June 6 - 8 Beethoven's Ninth 8 PM

June 9 Ode to Joy 3 PM

June 21 Super Swim Lesson 6 PM

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